CRP antibody

Catalog No. ABIN302074

Product Details anti-CRP Antibody

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRP antibody is un-conjugated

Application: ELISA

Specificity: The mouse monoclonal antibody C7 recognizes human CRP, a 117 kDa acute phase protein, it detects the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Purified human CRP

Clone: C7

Isotype: IgG1

Application Details

Application Notes: ELISA: The antibody C7 has been tested as the detection antibody in a sandwich ELISA for analysis of human C-Reactive Protein in combination with the antibody C5 (cat. no. 11-480-C100).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-CRP antibody (ABIN302074)

Krämer, Kess, Kremmer, Schulte-Hostede: "Multi-parameter determination of TNF?, PCT and CRP for point-of-care testing." in: The Analyst, Vol. 136, Issue 4, pp. 692-5, (2011) (PubMed).

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: C-Reactive Protein (CRP Products)

Synonyms: PTX1 antibody, crp antibody, AI255847 antibody, Aa1249 antibody, Ab1-341 antibody, Ab2-196 antibody, Ac1-114 antibody, Ac1262 antibody, Ac2-069 antibody, Ba2-693 antibody, APCS antibody, 0610010I23Rik antibody, AW743261 antibody, C77570 antibody, CRP2 antibody, CRP4 antibody, Crp antibody, ESP1 antibody, Hlp antibody, CRP5.1 antibody, zgc:152809 antibody, C-reactive protein antibody, C-reactive protein, pentraxin-related antibody, c-reactive protein, pentraxin-related antibody, cysteine rich protein 2 antibody, CRP antibody, crp antibody, Crp antibody, Crip2 antibody, LOC776376 antibody

Background: C-reactive protein,The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein composed of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa, physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.

Gene ID: 1401

UniProt: P02741

Pathways: Carbohydrate Homeostasis