Angiopoietin 2 antibody (AA 197-496)

Catalog No. ABIN3021112

This Rabbit Polyclonal antibody specifically detects Angiopoietin 2 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Angiopoietin 2 antibody (AA 197-496) (ABIN3021112)

Target: Angiopoietin 2 (ANGPT2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Angiopoietin 2 Antibody

Binding Specificity: AA 197-496

Sequence: AMEDKHIIQL QSIKEEKDQL QVLVSKQNSI IEELEKKIVT ATVNNSVLQK QQHDLMETVN NLLTMMSTSN SAKDPTVAKE EQISFRDCAE VFKSGHTTNG IYTLTFPNST EEIKAYCDME AGGGGWTIIQ RREDGSVDFQ RTWKEYKVGF GNPSGEYWLG NEFVSQLTNQ QRYVLKIHLK DWEGNEAYSL YEHFYLSSEE LNYRIHLKGL TGTAGKISSI SQPGNDFSTK DGDNDKCICK CSQMLTGGWW FDACGPSNLN GMYYPQRQNT NKFNGIKWYY WKGSGYSLKA TTMMIRPADF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 197-496 of human ANGPT2 (NP_001138.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Alternative Name: ANGPT2

Background: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.,ANGPT2,AGPT2,ANG2,Cell Biology & Developmental Biology,Growth factor,Cardiovascular,Angiogenesis,ANGPT2

Molecular Weight: 50 kDa/56 kDa

Gene ID: 285

UniProt: O15123

Pathways: RTK Signaling