Hexokinase 1 antibody (AA 20-300)

Catalog No. ABIN3021309

This anti-Hexokinase 1 antibody is a Rabbit Polyclonal antibody detecting Hexokinase 1 in WB, IHC, IP and IF. Suitable for Human.

Quick Overview for Hexokinase 1 antibody (AA 20-300) (ABIN3021309)

Target: Hexokinase 1 (HK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hexokinase 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-Hexokinase 1 Antibody

Binding Specificity: AA 20-300

Sequence: KKIDKYLYAM RLSDETLIDI MTRFRKEMKN GLSRDFNPTA TVKMLPTFVR SIPDGSEKGD FIALDLGGSS FRILRVQVNH EKNQNVHMES EVYDTPENIV HGSGSQLFDH VAECLGDFME KRKIKDKKLP VGFTFSFPCQ QSKIDEAILI TWTKRFKASG VEGADVVKLL NKAIKKRGDY DANIVAVVND TVGTMMTCGY DDQHCEVGLI IGTGTNACYM EELRHIDLVE GDEGRMCINT EWGAFGDDGS LEDIRTEFDR EIDRGSLNPG KQLFEKMVSG M

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human HK1 (NP_000179.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Hexokinase 1

Target: Hexokinase 1 (HK1)

Alternative Name: HK1

Background: Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.,HK1,HK,HK1-ta,HK1-tb,HK1-tc,HKD,HKI,HMSNR,HXK1,hexokinase,RP79,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Warburg Effect,Cardiovascular,Blood,Heart,Cardiac metabolism,HK1

Molecular Weight: 101 kDa/102 kDa

Gene ID: 3098

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effect