FHIT antibody (AA 25-147)

Catalog No. ABIN3021692

This Rabbit Polyclonal antibody specifically detects FHIT in WB. It exhibits reactivity toward Human.

Quick Overview for FHIT antibody (AA 25-147) (ABIN3021692)

Target: FHIT (Fragile Histidine Triad (FHIT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FHIT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FHIT Antibody

Binding Specificity: AA 25-147

Sequence: LVNRKPVVPG HVLVCPLRPV ERFHDLRPDE VADLFQTTQR VGTVVEKHFH GTSLTFSMQD GPEAGQTVKH VHVHVLPRKA GDFHRNDSIY EELQKHDKED FPASWRSEEE MAAEAAALRV YFQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-147 of human FHIT (NP_001159715.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FHIT

Target: FHIT (Fragile Histidine Triad (FHIT))

Alternative Name: FHIT

Background: This gene, a member of the histidine triad gene family, encodes a diadenosine 5',5'''-P1,P3-triphosphate hydrolase involved in purine metabolism. The gene encompasses the common fragile site FRA3B on chromosome 3, where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene. In fact, aberrant transcripts from this gene have been found in about half of all esophageal, stomach, and colon carcinomas. Alternatively spliced transcript variants have been found for this gene.,FHIT,AP3Aase,FRA3B,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,FHIT

Molecular Weight: 16 kDa

Gene ID: 2272

UniProt: P49789