CD6 antibody

Catalog No. ABIN3024446

This Mouse Monoclonal antibody specifically detects CD6 in FACS and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CD6 antibody (ABIN3024446)

Target: CD6

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: SPV-L14

Product Details anti-CD6 Antibody

Purpose: CD6 Antibody

Purification: Protein G affinity chromatography

Immunogen: A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the CD6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD6

Target: CD6

Alternative Name: CD6

Background: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

UniProt: P30203