UCHL1 antibody

Catalog No. ABIN3026781

The Mouse Monoclonal anti-UCHL1 antibody has been validated for WB and IF. It is suitable to detect UCHL1 in samples from Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio) and Sheep.

Quick Overview for UCHL1 antibody (ABIN3026781)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Reactivity: Human, Rat, Mouse, Cow, Pig, Guinea Pig, Rabbit, Dog, Zebrafish (Danio rerio), Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 13C4

Product Details anti-UCHL1 Antibody

Characteristics: This antibody specifically reacts with a protein of 20-30 kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.

Purification: Protein G affinity chromatography

Immunogen: Native protein from brain was used as the immunogen for this UchL1 antibody.

Isotype: IgG2a kappa

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the UchL1 antibody to be titered up or down for optimal performance.\. WB: 0.5-1 μg/mL,IF: 1-2 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the UchL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: UchL1 PGP9.5

Background: This antibody specifically reacts with a protein of 20-30  kDa, identified as UchL1 (Ubiquitin carboxyl-terminal hydrolase-1), or PGP9.5. Studies using UchL1 antibody have shown that expression is related to tumor progression, with high expression correlating with poor prognosis, making the protein a potentially useful marker for pancreatic and invasive colorectal cancer. A mutation in gene is believed to cause a form of Parkinson's disease.

Gene ID: 7345

Pathways: Feeding Behaviour