Prothrombin antibody (AA 600-612)
-
- Target See all Prothrombin (F2) Antibodies
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
-
Binding Specificity
- AA 600-612
-
Reactivity
- Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This Prothrombin antibody is un-conjugated
-
Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogen
- Amino acids 600-612 (THVFRLKRWMQKV-rat) were used as the immunogen for this Prothrombin antibody.
- Isotype
- IgG
- Top Product
- Discover our top product F2 Primary Antibody
-
-
- Application Notes
- Titration of the Prothrombin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
- Restrictions
- For Research Use only
-
- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the Prothrombin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- Target
- Prothrombin (F2) (Coagulation Factor II (thrombin) (F2))
- Alternative Name
- Prothrombin (Thrombin) (F2 Products)
- Synonyms
- PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, zgc:66319 antibody, wu:fb57c10 antibody, wu:fd42e09 antibody, wu:fd59d01 antibody, prothrombin antibody, F2 antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, coagulation factor II (thrombin) antibody, F2 antibody, f2 antibody
- Background
- F2 (Coagulation Factor II), also known as prothrombin and thrombin, is a serine protease that in humans is encoded by the F2 gene. The activated thrombin enzyme plays an important role in hemostasis and thrombosis: it converts fibrinogen to fibrin for blood clot formation, stimulates platelet aggregation, and activates coagulation factors V, VIII(F8), and XIII(F13A1). Thrombin also inhibits coagulation by Activating protein C.
- UniProt
- P18292
- Pathways
- Complement System, Peptide Hormone Metabolism, Regulation of G-Protein Coupled Receptor Protein Signaling
-