DOT1L antibody (AA 1390-1420)

Catalog No. ABIN3028622

Product Details anti-DOT1L Antibody

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Binding Specificity: AA 1390-1420

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOT1L antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Purification: Purified

Immunogen: A portion of amino acids 1390-1420 from the human protein was used as the immunogen for this KMT4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the KMT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the KMT4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for DOT1L

Target: DOT1L (DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))

Alternative Name: KMT4 (DOT1L Products)

Background: KMT4 is a histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. [UniProt]

UniProt: Q8TEK3