SOCS1 antibody (C-Term)
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- Target See all SOCS1 Antibodies
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOCS1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Antigen affinity
- Immunogen
- An amino acid sequence from the C-terminus of human SOCS1 (NPVLRDYLSSFPFQI) was used as the immunogen for this SOCS1 antibody (100% homologous in human, mouse and rat).
- Isotype
- IgG
- Top Product
- Discover our top product SOCS1 Primary Antibody
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anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodyVerified SOCS1 Reactivity: Human, Mouse ELISA, IHC, IF, FACS Host: Goat Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66), (N-Term) antibodySOCS1 Reactivity: Mouse, Rat WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB17347 unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibodySOCS1 Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Dog, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66) antibodySOCS1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibodySOCS1 Reactivity: Human WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 121-211) antibodySOCS1 Reactivity: Human ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibodySOCS1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibodySOCS1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 21-70) antibodySOCS1 Reactivity: Human, Mouse, Rat, Cow, Pig, Rabbit, Bat WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- The stated application concentrations are suggested starting amounts. Titration of the SOCS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Storage
- -20 °C
- Storage Comment
- After reconstitution, the SOCS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
- Alternative Name
- SOCS1 (SOCS1 Products)
- Background
- Suppressor of cytokine signaling 1(SOCS1), also known as Jak-binding protein(JAB), is a negative regulator to a subset of protein-tyrosine kinases. This 211-amino acid protein has a molecular mass of about 23.5 kD. The TEC-binding region of SOCS1 resides in the N terminus. SOCS1 associates with Tec and suppresses its kinase activity. The SOCS1 gene is intronless and is mapped to on chromosome 16p13.13. SOCS1 regulates the JAK/STAT signal-transduction pathway. Moreover, it contributes to protection against hepatic injury and fibrosis, and may also protect against hepatocarcinogenesis.
- UniProt
- O15524
- Pathways
- JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling, Response to Growth Hormone Stimulus
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