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IRAK3 antibody (C-Term)

IRAK3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031495
  • Target See all IRAK3 Antibodies
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Binding Specificity
    • 15
    • 9
    • 8
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 36
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 79
    • 7
    • 1
    Rabbit
    Clonality
    • 72
    • 15
    Polyclonal
    Conjugate
    • 39
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRAK3 antibody is un-conjugated
    Application
    • 72
    • 39
    • 13
    • 13
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human IRAKM (WFPKYIVPSQDLRPYKVNID) was used as the immunogen for this IRAKM antibody.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IRAK3 Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting points. Titration of the IRAKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the IRAKM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
    Alternative Name
    IRAKM (IRAK3 Products)
    Synonyms
    IRAK3 antibody, si:dkey-150i15.2 antibody, ASRT5 antibody, IRAKM antibody, IrakM antibody, 4833428C18Rik antibody, AI563835 antibody, IRAK-M antibody, interleukin 1 receptor associated kinase 3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IRAK3 antibody, irak3 antibody, Irak3 antibody
    Background
    Interleukin-1 receptor-associated kinase 3, also called IRAK3 or IRAKM is an enzyme that in humans is encoded by the IRAK3 gene. The IRAKM gene consists of 12 exons spanning a region of approximately 60 kb in chromosome 12q14.3. This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma.
    UniProt
    Q9Y616
    Pathways
    TLR Signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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