JUP antibody (N-Term)

Catalog No. ABIN3031517

The Rabbit Polyclonal anti-JUP antibody has been validated for WB. It is suitable to detect JUP in samples from Human, Mouse and Rat.

Quick Overview for JUP antibody (N-Term) (ABIN3031517)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-JUP Antibody

Binding Specificity: N-Term

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human gamma Catenin (LLATQVEGQATNLQRLAE) was used as the immunogen for this gamma Catenin antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the gamma Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the gamma Catenin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: gamma Catenin

Background: Catenin gamma, also known as Junction plakoglobin (JUP) or Plakoglobin (PKGB), is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Catenin beta and gamma, vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Catenin gamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location