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Pleiotrophin antibody (C-Term)

PTN Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3032264
$635.25
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target See all Pleiotrophin (PTN) Antibodies
    Pleiotrophin (PTN)
    Binding Specificity
    • 14
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 69
    • 41
    • 40
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 80
    • 7
    • 7
    • 2
    Rabbit
    Clonality
    • 89
    • 7
    Polyclonal
    Conjugate
    • 36
    • 13
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This Pleiotrophin antibody is un-conjugated
    Application
    • 51
    • 36
    • 30
    • 26
    • 21
    • 17
    • 8
    • 6
    • 6
    • 5
    • 2
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human Pleiotrophin (QAESKKKKKEGKKQEKMLD) was used as the immunogen for this Pleiotrophin antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the Pleiotrophin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the Pleiotrophin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    Pleiotrophin (PTN)
    Alternative Name
    Pleiotrophin (PTN Products)
    Synonyms
    zHBNF antibody, zgc:111787 antibody, harp antibody, hbnf antibody, X-PTF antibody, hbgf8 antibody, negf1 antibody, ptn antibody, PTN antibody, HARP antibody, HBGF8 antibody, HBNF antibody, NEGF1 antibody, PTN-A antibody, HB-GAM antibody, HBBM antibody, HBGF-8 antibody, OSF-1 antibody, HBBN antibody, OSF antibody, Osf-1 antibody, Osf1 antibody, Hbnf antibody, pleiotrophin antibody, pleiotrophin L homeolog antibody, ptn antibody, PTN antibody, ptn.L antibody, Ptn antibody
    Background
    Pleiotrophin(PTN) also known as heparin-binding brain mitogen(HBBM) or heparin-binding growth factor 8(HBGF-8) or neurite growth-promoting factor 1(NEGF1) or heparin affinity regulatory peptide(HARP) or heparin binding growth associated molecule(HB-GAM) is a protein that in humans is encoded by the PTN gene. PTN is the first member of a family of developmentally regulated cytokines. The PTN gene is mapped to 7q33-q34. A mutant PTN that contained only the first N-terminal 40 amino acids was a dominant negative. Pleiotrophin is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. Pleiotrophin binds to cell-surface nucleolin as a low affinity receptor. This binding can inhibit HIV infection.
    UniProt
    P21246
    Pathways
    RTK Signaling
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