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TTR antibody (AA 21-147)

TTR Reactivity: Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3042346
  • Target See all TTR Antibodies
    TTR (Transthyretin (TTR))
    Binding Specificity
    • 32
    • 16
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-147
    Reactivity
    • 101
    • 32
    • 28
    • 6
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Mouse, Rat
    Host
    • 116
    • 23
    • 11
    • 7
    • 3
    • 1
    • 1
    Rabbit
    Clonality
    • 127
    • 35
    Polyclonal
    Conjugate
    • 67
    • 29
    • 25
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TTR antibody is un-conjugated
    Application
    • 110
    • 67
    • 56
    • 26
    • 21
    • 14
    • 13
    • 12
    • 11
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Transthyretin(TTR) detection. Tested with WB, IHC-P in Mouse,Rat.
    Gene Name: transthyretin
    Protein Name: Transthyretin
    Purification
    Immunogen affinity purified.
    Immunogen
    E.coli-derived rat Prealbumin recombinant protein (Position: G21-N147). Rat Prealbumin shares 94.5% amino acid (aa) sequence identity with mouse Prealbumin.
    Isotype
    IgG
    Top Product
    Discover our top product TTR Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    TTR (Transthyretin (TTR))
    Alternative Name
    TTR (TTR Products)
    Synonyms
    zgc:103583 antibody, TTR antibody, LOC100226992 antibody, CTS antibody, CTS1 antibody, HsT2651 antibody, PALB antibody, TBPA antibody, AA408768 antibody, AI787086 antibody, D17860 antibody, prealbumin antibody, Lr1 antibody, Tbpa antibody, Prealbumin antibody, xTTR antibody, transthyretin (prealbumin, amyloidosis type I) antibody, transthyretin antibody, Transthyretin antibody, transthyretin (prealbumin, amyloidosis type 1) antibody, transthyretin-like antibody, transthyretin L homeolog antibody, ttr antibody, TTR antibody, vpb38 antibody, MRAD2831_RS38185 antibody, Caci_4246 antibody, LOC100226992 antibody, Ttr antibody, ttr.L antibody
    Background
    Transthyretin (TTR) is also known as prealbumin. It is mapped to chromosome region 18q11.2-q12.1. This gene encodes a carrier protein responsible for the transport of thyroid hormones and retinol. The protein consists of a tetramer of identical subunits. Due to increased stability of the tetramer form of this encoded protein in mouse, compared to the human protein, this gene product has a reduced tendency to form amyloid fibrils. In humans, this protein binds beta-amyloid preventing its aggregation and providing a neuroprotective role in Alzheimer's disease.

    Synonyms: Amyloid polyneuropathy antibody|Amyloidosis I antibody|ATTR antibody|Carpal tunnel syndrome 1 antibody|CTS antibody|CTS1 antibody| Dysprealbuminemic euthyroidal hyperthyroxinemia antibody|Dystransthyretinemic hyperthyroxinemia antibody|Epididymis luminal protein 111 antibody|HEL111 antibody|HsT2651 antibody|PALB antibody|Prealbumin amyloidosis type I antibody|Prealbumin antibody|Prealbumin Thyroxine-binding antibody|Senile systemic amyloidosis antibody|TBPA antibody|Thyroxine binding prealbumin antibody|Transthyretin antibody|TTHY_HUMAN antibody|TTR antibody|TTR protein antibody
    Gene ID
    24856
    UniProt
    P02767
    Pathways
    Hormone Transport
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