Caspase 7 antibody (AA 117-198)
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- Target See all Caspase 7 (CASP7) Antibodies
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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Binding Specificity
- AA 117-198
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purpose
- Rabbit IgG polyclonal antibody for Caspase-7(CASP7) detection. Tested with WB, IHC-P in Human,Rat.
- Cross-Reactivity (Details)
- No cross reactivity with other proteins.
- Characteristics
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Rabbit IgG polyclonal antibody for Caspase-7(CASP7) detection. Tested with WB, IHC-P in Human,Rat.
Gene Name: caspase 7, apoptosis-related cysteine peptidase
Protein Name: Caspase-7 - Purification
- Immunogen affinity purified.
- Immunogen
- E.coli-derived human Caspase-7 recombinant protein (Position: A117-D198). Human Caspase-7 shares 92.7% amino acid (aa) sequence identity with both mouse and rat Caspase-7.
- Isotype
- IgG
- Top Product
- Discover our top product CASP7 Primary Antibody
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for Caspase-7 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
- Alternative Name
- CASP7 (CASP7 Products)
- Synonyms
- xCaspase-7 antibody, caspase-7 antibody, caspase7 antibody, cmh-1 antibody, ice-lap3 antibody, mch3 antibody, CASP7 antibody, AI314680 antibody, CMH-1 antibody, ICE-IAP3 antibody, Mch3 antibody, mCASP-7 antibody, CASP-7 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody, Caspase-7 antibody, MCH3/SCA-2 antibody, SCA-2 antibody, caspase 7 antibody, caspase-7 antibody, caspase 7 S homeolog antibody, CASP7 antibody, xcaspase-7 antibody, casp7 antibody, casp7.S antibody, Casp7 antibody
- Background
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CASP7, Caspase-7, apoptosis-related cysteine peptidase, is a human protein encoded by the CASP7 gene. CASP7 orthologs have been identified in nearly all mammals for which complete genome data are available. CASP7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Using radiation hybrid mapping, the CASP7 gene was localized to human chromosome 10q25.1-q25.2. The orderly activation of CASP7 regulates microglia activation through a protein kinase C-delta (PRKCD)-dependent pathway.
Synonyms: Apoptosis related cysteine peptidase antibody|Apoptosis Related Cysteine Protease antibody|Apoptosis Related Cysteine Protease antibody|Apoptotic protease Mch-3 antibody|Apoptotic Protease MCH3 antibody|Apoptotic Protease MCH3 antibody|CASP 7 antibody|CASP-7 antibody|CASP7 antibody|CASP7_HUMAN antibody|Caspase 7 antibody|Caspase 7 apoptosis related cysteine peptidase antibody|Caspase-7 subunit p11 antibody|Caspase7 antibody|CMH 1 antibody|CMH-1 antibody|CMH1 antibody|CMH1 antibody|ICE LAP3 antibody|ICE like Apoptotic Protease 3 antibody|ICE-LAP3 antibody|ICE-like apoptotic protease 3 antibody|LICE2 antibody|MCH3 antibody|MCH3 antibody - Gene ID
- 840
- UniProt
- P55210
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
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