Glutamate Receptor 3 antibody (AA 29-360)

Catalog No. ABIN3042428

Product Details anti-Glutamate Receptor 3 Antibody

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Binding Specificity: AA 29-360

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Glutamate receptor 3(GRIA3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutamate receptor, ionotropic, AMPA 3
Protein Name: Glutamate receptor 3

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GRIA3 recombinant protein (Position: G29-M360). Human GRIA3 shares 99% amino acid (aa) sequence identity with both mouse and rat GRIA3.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for GRIA3 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Glutamate Receptor 3

Target: Glutamate Receptor 3 (GRIA3) (Glutamate Receptor, Ionotropic, AMPA 3 (GRIA3))

Alternative Name: GRIA3 (GRIA3 Products)

Synonyms: AMPA antibody, gria3 antibody, GRIN3A antibody, glur3b antibody, gria3.2 antibody, zfGRIA3[b] antibody, si:bz1o18.1 antibody, SI:zC231H1.1 antibody, si:zc140k5.3 antibody, GLUR3 antibody, GLUR-C antibody, GLUR3/C antibody, GRIA3 antibody, glur3 antibody, GluA3 antibody, GluR-3 antibody, GluR-C antibody, GluR-K3 antibody, GLUR-K3 antibody, GLURC antibody, MRX94 antibody, 2900064I19Rik antibody, Glur-3 antibody, Glur3 antibody, Gluralpha3 antibody, glutamate receptor, ionotropic, AMPA 3b antibody, glutamate ionotropic receptor AMPA type subunit 3 antibody, glutamate receptor, ionotropic, AMPA 3 antibody, glutamate receptor, ionotropic, AMPA 3 L homeolog antibody, glutamate receptor, ionotropic, AMPA3 (alpha 3) antibody, gria3b antibody, GRIA3 antibody, gria3 antibody, gria3.L antibody, Gria3 antibody

Background: Glutamate receptor 3 is a protein that in humans is encoded by the GRIA3 gene. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. It is mapped to Xq25. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists.

Synonyms: AMPA 3 antibody|AMPA selective glutamate receptor 3 antibody|AMPA-selective glutamate receptor 3 antibody|dJ1171F9.1 antibody|GluA3 antibody|GLUK3 antibody|GLUR 3 antibody|GLUR C antibody|GLUR K3 antibody|GluR-3 antibody|GluR-C antibody|GluR-K3 antibody|GLUR3 antibody|GLURC antibody|Glutamate receptor 3 antibody|Glutamate receptor C antibody|Glutamate Receptor Ionotrophic AMPA 3 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor subunit 3 antibody|GRIA 3 antibody|Gria3 antibody|GRIA3_HUMAN antibody|GRM 3 antibody|Ionotrophic Glutamate Receptor antibody|Metabotropic glutamate receptor 3 precursor antibody|mGlu 3 antibody|MGLUR 3 antibody|MRX94 antibody

Gene ID: 2892

UniProt: P42263

Pathways: PI3K-Akt Signaling, cAMP Metabolic Process, Synaptic Membrane