CYLD antibody (AA 618-956)

Catalog No. ABIN3042782

Product Details anti-CYLD Antibody

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Binding Specificity: AA 618-956

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYLD antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase CYLD(CYLD) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Ubiquitin carboxyl-terminal hydrolase CYLD(CYLD) detection. Tested with WB in Human,Rat.
Gene Name: cylindromatosis (turban tumor syndrome)
Protein Name: Ubiquitin carboxyl-terminal hydrolase CYLD

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CYLD

Target: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Alternative Name: CYLD (CYLD Products)

Synonyms: BRSS antibody, CDMT antibody, CYLD1 antibody, CYLDI antibody, EAC antibody, MFT antibody, MFT1 antibody, SBS antibody, TEM antibody, USPL2 antibody, 2010013M14Rik antibody, 2900009M21Rik antibody, C130039D01Rik antibody, mKIAA0849 antibody, cyld antibody, LRRGT00003 antibody, Rp1 antibody, Rp1h antibody, CYLD lysine 63 deubiquitinase antibody, cylindromatosis (turban tumor syndrome), a antibody, CYLD antibody, Cyld antibody, cylda antibody

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Synonyms: BRSS antibody|CDMT antibody|Cyld antibody|CYLD gene antibody|CYLD_HUMAN antibody|CYLD1 antibody|CYLDI antibody|cylindromatosis (turban tumor syndrome) antibody|cylindromatosis 1 antibody|Deubiquitinating enzyme CYLD antibody|EAC antibody|HSPC057 antibody|KIAA0849 antibody|MFT antibody|MFT1 antibody|Probable ubiquitin carboxyl terminal hydrolase CYLD antibody|SBS antibody|TEM antibody|turban tumor syndrome antibody|Ubiquitin carboxyl-terminal hydrolase CYLD antibody|ubiquitin specific peptidase like 2 antibody|ubiquitin thioesterase CYLD antibody|Ubiquitin thiolesterase CYLD antibody|Ubiquitin-specific processing protease CYLD antibody|Ubiquitin-specific-processing protease CYLD antibody| USPL2 antibody

Gene ID: 1540

Pathways: Apoptosis, Activation of Innate immune Response