TIA1 antibody (N-Term)

Catalog No. ABIN3042843

Product Details anti-TIA1 Antibody

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Binding Specificity: AA 98-110, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Nucleolysin TIA-1 isoform p40(TIA1) detection. Tested with WB in Human,Mouse.

Sequence: STQRSQDHFH VFV

Cross-Reactivity (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Nucleolysin TIA-1 isoform p40(TIA1) detection. Tested with WB in Human,Mouse.
Gene Name: TIA1 cytotoxic granule-associated RNA binding protein
Protein Name: Nucleolysin TIA-1 isoform p40

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TIA1(98-110aa STQRSQDHFHVFV), identical to the related mouse sequence.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TIA1

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Alternative Name: TIA1 (TIA1 Products)

Synonyms: tia1 antibody, 2310050N03Rik antibody, AI256674 antibody, TIA-1 antibody, mTIA-1 antibody, WDM antibody, TIAL1 antibody, TIAR antibody, tia-1 antibody, nucleolysin TIA-1 isoform p40 antibody, hypothetical protein antibody, nucleolysin TIAR antibody, nucleolysin tia-1 antibody, nucleolysin TIA-1 antibody, cytotoxic granule-associated RNA binding protein 1 antibody, TIA1 cytotoxic granule associated RNA binding protein antibody, TIA1 cytotoxic granule-associated RNA binding protein antibody, TIA1 cytotoxic granule-associated RNA binding protein L homeolog antibody, PTRG_10065 antibody, PGTG_08590 antibody, LOC5568274 antibody, CpipJ_CPIJ013665 antibody, VDBG_07004 antibody, MGYG_03339 antibody, Tsp_15456 antibody, tia1 antibody, Tia1 antibody, TIA1 antibody, tia1.L antibody

Background: TIA1, also called WDM, encodes an RNA-binding protein involved in splicing regulation and translational repression. The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte(CTL) target cells. By in situ hybridization, this gene is mapped to chromosome 2p13.3. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is though to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.

Synonyms: Cytotoxic granule associated RNA binding protein 1 antibody|Cytotoxic granule associated RNA binding protein antibody|mTIA-1 antibody|Nucleolysin TIA 1 isoform p40 antibody|Nucleolysin TIA-1 isoform p40 antibody|Nucleolysin TIA1 isoform p40 antibodyp40 TIA 1 antibody|p40-TIA-1(containing p15-TIA-1) antibody|p40-TIA-1 antibody|RNA binding protein TIA 1 antibody|RNA binding protein TIA1 antibody|RNA-binding protein TIA-1 antibody|T-cell-restricted intracellular antigen-1 antibody|TIA 1 antibody|TIA 1 cytotoxic granule associated RNA binding protein antibody|Tia antibody|TIA-1 antibody|TIA1 antibody|TIA1 cytotoxic granule associated RNA binding protein antibody|TIA1 cytotoxic granule associated RNA binding protein like 1 antibody|TIA1 protein antibody|TIA1_HUMAN antibody|TIAL1 antibody|TIAR antibody

UniProt: P31483