Surfactant Protein A1 antibody (C-Term)

Catalog No. ABIN3043205

There are 5+ publications for this product available. The Rabbit Polyclonal anti-Surfactant Protein A1 antibody is suitable to detect Surfactant Protein A1 in samples from Rat and Mouse. It has been validated for WB and IHC.

Quick Overview for Surfactant Protein A1 antibody (C-Term) (ABIN3043205)

Target: Surfactant Protein A1 (SFTPA1)

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Surfactant Protein A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Surfactant Protein A1 Antibody

Binding Specificity: C-Term

Purpose: Anti-SFTPA1 Antibody

Sequence: WNDKGCLQYR LAICEF

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related rat sequence.

Characteristics: Anti-SFTPA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse SFTPA1, identical to the related rat sequence.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Mouse Western blot, 0.1-0.5 μg/mL, Mouse, Rat

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

References for anti-Surfactant Protein A1 antibody (ABIN3043205)

Ostermann, Seeliger, David, Flasche, Maus, Reinboth, Christmann, Neumann, Brand, Seltmann, Bühling, Paton, Roth, Vogl, Viemann, Welte, Maus: "S100A9 is indispensable for survival of pneumococcal pneumonia in mice." in: PLoS pathogens, Vol. 19, Issue 7, pp. e1011493, (2023) (PubMed).

Ostermann, Maus, Stolper, Schütte, Katsarou, Tumpara, Pich, Mueller, Janciauskiene, Welte, Maus: "Alpha-1 antitrypsin deficiency impairs lung antibacterial immunity in mice." in: JCI insight, Vol. 6, Issue 3, (2021) (PubMed).

Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

Zhou, Chen, Jiang, Feng, Han: "Effects of bone marrow-derived mesenchymal stem cells transfected with survivin on pulmonary fibrosis in mice." in: Experimental and therapeutic medicine, Vol. 10, Issue 5, pp. 1857-1864, (2015) (PubMed).

Wu, You, Ma, Li, Yuan, Li, Ye, Liu, Yao, Chen, Lai, Yang: "Role of transient receptor potential ion channels and evoked levels of neuropeptides in a formaldehyde-induced model of asthma in BALB/c mice." in: PLoS ONE, Vol. 8, Issue 5, pp. e62827, (2013) (PubMed).

Target Details for Surfactant Protein A1

Target: Surfactant Protein A1 (SFTPA1)

Alternative Name: SFTPA1

Background:

Background: Surfactant protein A is an innate immune system collectin. The gene encoding SP-A map to mouse chromosome 14. Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Gene Full Name: Pulmonary surfactant-associated protein A

Sequence Similarities: Belongs to the SFTPA family.

Molecular Weight: 26-35 kDa

Gene ID: 20387

UniProt: P35242