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IL2 Receptor beta antibody (C-Term)

IL2RB Reactivity: Mouse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3043246
  • Target See all IL2 Receptor beta (IL2RB) Antibodies
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Binding Specificity
    • 29
    • 16
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 503-539, C-Term
    Reactivity
    • 92
    • 76
    • 16
    • 5
    • 1
    Mouse
    Host
    • 84
    • 25
    • 21
    Rabbit
    Clonality
    • 85
    • 44
    • 1
    Polyclonal
    Conjugate
    • 61
    • 10
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This IL2 Receptor beta antibody is un-conjugated
    Application
    • 72
    • 55
    • 38
    • 26
    • 26
    • 17
    • 14
    • 10
    • 10
    • 8
    • 7
    • 7
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit beta(IL2RB) detection. Tested with WB in Mouse.
    Sequence
    NLHGQDQDRG QGPILTLNTD AYLSLQELQA QDSVHLI
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Interleukin-2 receptor subunit beta(IL2RB) detection. Tested with WB in Mouse.
    Gene Name: interleukin 2 receptor, beta
    Protein Name: Interleukin-2 receptor subunit beta
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse IL2RB (503-539aa NLHGQDQDRGQGPILTLNTDAYLSLQELQAQDSVHLI), different from the related human sequence by sixteen amino acids, and from the related rat sequence by fourteen amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product IL2RB Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Alternative Name
    IL2RB (IL2RB Products)
    Synonyms
    IL2RB antibody, il-2rb antibody, CD122 antibody, IL15RB antibody, P70-75 antibody, IL2RBC antibody, IL-15Rbeta antibody, IL15Rbeta antibody, Il-2/15Rbeta antibody, Il-2Rbeta antibody, p70 antibody, interleukin 2 receptor subunit beta antibody, interleukin-2 receptor subunit beta antibody, interleukin 2 receptor, beta antibody, interleukin 2 receptor, beta chain antibody, IL2RB antibody, LOC510185 antibody, il2rb antibody, Il2rb antibody
    Background
    IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.

    Synonyms: CD 122 antibody|CD122 antibody|CD122 antigen antibody|High affinity IL 2 receptor beta subunit antibody|High affinity IL 2 receptor subunit beta antibody|High affinity IL-2 receptor subunit beta antibody|High affinity IL2 receptor beta subunit antibody|High affinity IL2 receptor subunit beta antibody|IL 2 receptor antibody|IL-2 receptor subunit beta antibody|IL-2R subunit beta antibody|IL-2RB antibody|IL15RB antibody|IL2 R B antibody|IL2 RB antibody|IL2 receptor antibody|IL2RB antibody|IL2RB_HUMAN antibody|Interleukin 2 receptor beta antibody|Interleukin 2 receptor subunit beta antibody|Interleukin-2 receptor subunit beta antibody|OTTHUMP00000028799 antibody|P70 75 antibody|P70-75 antibody|P7075 antibody|p75 antibody
    Gene ID
    16185
    UniProt
    P16297
    Pathways
    JAK-STAT Signaling, Growth Factor Binding
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