Prostate Specific Antigen antibody (AA 25-261)

Catalog No. ABIN3043283

Product Details anti-Prostate Specific Antigen Antibody

Target: Prostate Specific Antigen (PSA)

Binding Specificity: AA 25-261

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prostate Specific Antigen antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Prostate-specific antigen(KLK3) detection. Tested with WB in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Prostate-specific antigen(KLK3) detection. Tested with WB in Human,Rat.
Gene Name: kallikrein-related peptidase 3
Protein Name: Prostate-specific antigen

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human PSA recombinant protein (Position: I25-P261). Human PSA shares 54% amino acid (aa) sequence identity with rat PSA.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, The detection limit for PSA is approximately 0.2 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Alternative Name: KLK3 (PSA Products)

Background: Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. KLK3 is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland. This gene is mapped to 19q13.33. KLK3 is present in small quantities in the serum of men with healthy prostates, but is often elevated in the presence of prostate cancer or other prostate disorders. KLK3 is produced for the ejaculate where it liquifies the semen in the seminal coagulum and allows sperm to swim freely. It is also believed to be instrumental in dissolving the cervical mucous cap, allowing the entry of sperm. It is not a unique indicator of prostate cancer, but may also detect prostatitis or benign prostatic hyperplasia.

Synonyms: antigen, prostate-specific antibody|APS antibody|Gamma seminoprotein antibody|Gamma-seminoprotein antibody|hK3 antibody|Kallikrein 3 antibody|Kallikrein 3, (prostate specific antigen) antibody|Kallikrein related peptidase 3 antibody|Kallikrein-3 antibody|KLK 3 antibody|KLK2A1 antibody|KLK3 antibody|KLK3_HUMAN antibody|P 30 antigen antibody|P-30 antigen antibody|P30 antigen antibody|Prostate Specific Antigen antibody|Prostate-specific antigen antibody|PSA antibody|Semenogelase antibody|Seminin antibody

Gene ID: 354

UniProt: P07288

Pathways: Complement System