SGCA antibody (AA 24-387)

Catalog No. ABIN3043432

Product Details anti-SGCA Antibody

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Binding Specificity: AA 24-387

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGCA antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Alpha-sarcoglycan(SGCA) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Alpha-sarcoglycan(SGCA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: sarcoglycan, alpha (50 kDa dystrophin-associated glycoprotein)
Protein Name: Alpha-sarcoglycan

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human SGCA recombinant protein (Position: Q24-H387). Human SGCA shares 90.7% amino acid (aa) sequence identity with mouse SGCA.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SGCA

Target: SGCA (Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA))

Alternative Name: SGCA (SGCA Products)

Synonyms: Sgca antibody, 50-DAG antibody, A2 antibody, ADL antibody, DAG2 antibody, DMDA2 antibody, LGMD2D antibody, SCARMD1 antibody, adhalin antibody, 50DAG antibody, Asg antibody, sarcoglycan alpha antibody, sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody, sarcoglycan, alpha antibody, SGCA antibody, Sgca antibody

Background: Alpha-sarcoglycan is a protein that in humans is encoded by the SGCA gene. This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: 50 DAG antibody|50 kDa dystrophin associated glycoprotein antibody|50 kDa dystrophin-associated glycoprotein antibody|50DAG antibody|50kD DAG antibody|59 kDa antibody|A2 antibody|adhalin antibody|ADL antibody|Alpha SG antibody|Alpha-sarcoglycan antibody|Alpha-SG antibody|Asg antibody|DAG2 antibody|DMDA2 antibody|Dystroglycan 2 antibody|Dystroglycan-2 antibody|LGMD2D antibody|sarcoglycan, alpha (dystrophin-associated glycoprotein) antibody|SCARMD1 antibody|Sgca antibody|SGCA_HUMAN antibody

Gene ID: 6442

UniProt: Q16586