BIRC3 antibody (AA 1-191)

Catalog No. ABIN3043510

Product Details anti-BIRC3 Antibody

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Binding Specificity: AA 1-191

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BIRC3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 3(BIRC3) detection. Tested with WB in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Baculoviral IAP repeat-containing protein 3(BIRC3) detection. Tested with WB in Human.
Gene Name: baculoviral IAP repeat containing 3
Protein Name: Baculoviral IAP repeat-containing protein 3

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human cIAP2 recombinant protein (Position: M1-K191). Human cIAP2 shares 69.8% amino acid (aa) sequence identity with mouse cIAP2.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for BIRC3

Target: BIRC3 (Baculoviral IAP Repeat Containing 3 (BIRC3))

Alternative Name: BIRC3 (BIRC3 Products)

Synonyms: AIP1 antibody, API2 antibody, CIAP2 antibody, HAIP1 antibody, HIAP1 antibody, MALT2 antibody, MIHC antibody, RNF49 antibody, c-IAP2 antibody, Api1 antibody, Api2 antibody, IAP1 antibody, IAP2 antibody, MIHB antibody, Birc2 antibody, HIAP2 antibody, MIAP1 antibody, MIAP2 antibody, cIAP1 antibody, cIAP2 antibody, cIAP-1 antibody, cIAP-2 antibody, AW107670 antibody, BIRC2 antibody, baculoviral IAP repeat containing 3 antibody, baculoviral IAP repeat-containing 3 antibody, baculoviral IAP repeat-containing protein 3 antibody, inhibitor of apoptosis protein-2 antibody, BIRC3 antibody, Birc3 antibody, LOC100399118 antibody, OpmnVgp074 antibody

Background: Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Synonyms: AIP 1 antibody|AIP1 antibody|API 2 antibody|API2 antibody|API2 antibody|Apoptosis inhibitor 2 antibody|Baculoviral IAP repeat containing 3 antibody|Baculoviral IAP repeat containing protein 3 antibody|Baculoviral IAP repeat-containing protein 3 antibody|BIRC 3 antibody| BIRC3 antibody|BIRC3 antibody|BIRC3_HUMAN antibody|C IAP2 antibody|C-IAP2 antibody|CIAP 2 antibody|CIAP 2 antibody|CIAP2 antibody|HAIP 1 antibody|HAIP1 antibody|HAIP1 antibody|HIAP 1 antibody|HIAP-1 antibody|HIAP1 antibody|IAP homolog C antibody|IAP-1 antibody|Inhibitor of apoptosis protein 1 antibody|Inhibitor of apoptosis protein 1 antibody|MALT 2 antibody| MALT2 antibody|Mammalian IAP homolog C antibody|MIHC antibody|MIHC antibody|RING finger protein 49 antibody|RNF49 antibody|TNFR2 TRAF signaling complex protein 1 antibody|TNFR2 TRAF signalling complex protein antibody|TNFR2-TRAF-signaling complex protein 1 antibody

Gene ID: 330

UniProt: Q13489

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades