RAD51C antibody (Middle Region)

Catalog No. ABIN3043564

This Rabbit Polyclonal antibody specifically detects RAD51C in WB. It exhibits reactivity toward Human.

Quick Overview for RAD51C antibody (Middle Region) (ABIN3043564)

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD51C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAD51C Antibody

Binding Specificity: Middle Region

Purpose: Anti-Rad51C Antibody

Sequence: IQHLQLIAEK HKGEEHRKAL EDFTLDNILS H

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: different from the related mouse sequence by eight amino acids.

Characteristics: Anti-Rad51C Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Rad51C, different from the related mouse sequence by eight amino acids.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: RAD51C

Background:

Background: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Gene Full Name: RAD51 paralog C

Molecular Weight: 42 kDa

Gene ID: 5889

UniProt: O43502

Pathways: DNA Damage Repair