MAPK6 antibody (AA 520-721)

Catalog No. ABIN3043611

Product Details anti-MAPK6 Antibody

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Binding Specificity: AA 520-721

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAPK6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 6(MAPK6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Mitogen-activated protein kinase 6(MAPK6) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: mitogen-activated protein kinase 6
Protein Name: Mitogen-activated protein kinase 6

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MAPK6 recombinant protein (Position: E520-N721). Human MAPK6 shares 86.2% and 82.8% amino acid (aa) sequence identity with mouse and rat MAPK6, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for MAPK6

Target: MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

Alternative Name: MAPK6 (MAPK6 Products)

Synonyms: ERK3 antibody, HsT17250 antibody, PRKM6 antibody, p97MAPK antibody, 2610021I23Rik antibody, D130053K17Rik antibody, Erk3 antibody, Mapk4 antibody, Mapk63 antibody, Prkm4 antibody, Prkm6 antibody, ATMAPK6 antibody, ATMPK6 antibody, F18O19.10 antibody, MAP KINASE 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, SUSERK3 antibody, erk3 antibody, p97mapk antibody, si:ch211-235f12.1 antibody, mitogen-activated protein kinase 6 antibody, MAP kinase 6 antibody, MAPK6 antibody, Mapk6 antibody, MPK6 antibody, mapk6 antibody

Background: Mitogen-activated protein kinase 6 is an enzyme that in humans is encoded by the MAPK6 gene. It is mapped to 15q21. The protein encoded by this gene is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblastsupon treatment with serum or phorbol esters.

Synonyms: ERK-3 antibody|ERK3 antibody|Extracellular signal regulated kinase 3 antibody|Extracellular signal regulated kinase p97 antibody| Extracellular signal-regulated kinase 3 antibody|HsT17250 antibody|MAP kinase 6 antibody|MAP kinase isoform p97 antibody|MAPK 6 antibody|MAPK6 antibody|Mitogen activated protein kinase 6 antibody|Mitogen-activated protein kinase 6 antibody|MK06_HUMAN antibody| p97 MAPK antibody|p97-MAPK antibody|PRKM6 antibody|Protein kinase mitogen activated 5 antibody|Protein kinase mitogen activated 6 antibody

Gene ID: 5597

UniProt: Q16659

Pathways: MAPK Signaling, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C