p107 antibody

Catalog No. ABIN306628

This Mouse Monoclonal antibody specifically detects p107 in WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for p107 antibody (ABIN306628)

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This p107 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: KAB6

Product Details anti-p107 Antibody

Purpose: Mouse anti Human p107

Characteristics: P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Western Blots at 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for p107

Target: p107 (RBL1) (Retinoblastoma-Like 1 (p107) (RBL1))

Alternative Name: p107

Background: P107, Retinoblastoma-like protein 1, PRB1, 107 kda retinoblastoma-associated protein

UniProt: P28749, Q64701

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases