EPH Receptor B1 antibody (AA 620-1596)

Catalog No. ABIN306670

Product Details anti-EPH Receptor B1 Antibody

Target: EPH Receptor B1 (EPHB1)

Binding Specificity: AA 620-1596

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This EPH Receptor B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Rat

Characteristics: Eph B1 (ELK receptor) SAM, Tyrosine-protein kinase receptor EPH-2, Ephrin type B receptor 1, HEK6,Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicated during the process of spermiogenesis and in the actin-based stellate morphology of mesangial cells

Purification: Ammonium Sulfate Precipitation

Immunogen: Sheep were immunized with a recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blot (2-5 μg/mL), immunohistochemistry and immunoprecipitation. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Alternative Name: ELK rec tyr Kinase (Eph B1 SAM) (EPHB1 Products)

Synonyms: ELK antibody, EPHT2 antibody, Hek6 antibody, NET antibody, ephb1-a antibody, xek antibody, Xek antibody, MGC89790 antibody, EPHB1 antibody, CEK6 antibody, EK6 antibody, 9330129L11 antibody, AW488255 antibody, C130099E04Rik antibody, Cek6 antibody, ENSMUSG00000074119 antibody, Elk antibody, Elkh antibody, Net antibody, Ephb2 antibody, Erk antibody, elk antibody, EPH receptor B1 antibody, EPH receptor B1 S homeolog antibody, ephrin type-B receptor 1 antibody, Eph receptor B1 antibody, EPHB1 antibody, ephb1.S antibody, ephb1 antibody, LOC100467687 antibody, Ephb1 antibody

Pathways: RTK Signaling