Potassium Channel antibody

Catalog No. ABIN306719

The Rabbit Polyclonal anti-Potassium Channel antibody is suitable to detect Potassium Channel in samples from Rat. It has been validated for WB, IF and IP.

Quick Overview for Potassium Channel antibody (ABIN306719)

Target: Potassium Channel

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details

Purpose: Rabbit anti Rat Potassium Channel

Cross-Reactivity: Rat

Characteristics: Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to Icurrent in heart and current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits In response to membrane depolarization, Kv4.2 channels accumulate in the closed-inactivated state(s), from which they directly recover, bypassing the open state. Kv4.2 is a substrate for ERK in vitro and in vivo, and suggest that ERK may regulate potassium-channel function by direct phosphorylation of the pore-forming alpha subunit.

Purification: Ammonium Sulfate Precipitation

Isotype: IgG

Application Details

Application Notes: Optimal antibody concentration should be evaluated by serial dilutions. Suggested Western Blot dilution 1:1000. Other applications: Immunoprecipitation, immunofluorescence.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details

Target: Potassium Channel

Background: RK5, Shal1, Kcnd2, Potassium voltage-gated channel subfamily D member 2

UniProt: Q63881