Potassium Channel (pSer503) antibody
The Rabbit Polyclonal anti-Potassium Channel antibody (ABIN5688902) specifically detects Potassium Channel in WB and IHC.
The antibody is reactive with Rat and Mouse samples.
Catalog No. ABIN5688902
$742.50
Plus shipping costs $50.00
100 μL
Shipping to:
United States
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Quick Overview for Potassium Channel (pSer503) antibody (ABIN5688902)
Target
Potassium Channel
Reactivity
Rat, Mouse
Host
Rabbit
Clonality
Polyclonal
Conjugate
Un-conjugated
Application
Western Blotting (WB), Immunohistochemistry (IHC)
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Binding Specificity
- pSer503
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Purification
- Affinity Purified
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Immunogen
- Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser503 of the voltage-gated potassium channel Kv3.1, conjugated to keyhole limpet hemocyanin (KLH).
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Application Notes
- The antibody has been directly tested for reactivity in Western blots with rat and mouse tissue.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 100 μLin 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.
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Storage
- -20 °C
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Storage Comment
- Potassium Channel antibody can be stored at -20°C and is stable at -20°C for at least 1 year.
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- Potassium Channel
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Background
- Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995, Pongs, 1999, Blaine and Ribera, 1998, Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).
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Molecular Weight
- 100 kDa
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Gene ID
- 25327
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UniProt
- P25122
Target
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