MAP3K7 antibody (full length)

Catalog No. ABIN306727

This Sheep Polyclonal antibody specifically detects MAP3K7 in WB and IP. It exhibits reactivity toward Human.

Quick Overview for MAP3K7 antibody (full length) (ABIN306727)

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This MAP3K7 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-MAP3K7 Antibody

Binding Specificity: full length

Purpose: Sheep anti Human TAK1

Cross-Reactivity: Human

Characteristics: C-TAK1 (Cdc25C associated protein kinase) is a ubiquitously expressed protein kinase found in human tissues and cell lines and can phosphorylate Cdc25C on serine 216 in vitro. C-TAK1 is distinct from the DNA damage checkpoint kinase Chk1 and may regulate interactions between Cdc25C and 14-3-3 in vivo by phosphorylating Cdc25C at serine 216.

Purification: Ammonium Sulfate Precipitation

Immunogen: Recombinant, full-length His-tagged human C-TAK1 produced in E. Coli.

Isotype: IgG

Application Details

Application Notes: Antibody detects c-tak1 by Western blot analysis at 1 to 5 μg/mL. Detects c-tak1 in RKO and HCT116 cell lysates. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Alternative Name: TAK1

Background: Mark3, Sheep anti-Cdc25c associated protein kinase-1, human

UniProt: P27448

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway