BAG5 antibody

Catalog No. ABIN306923

The Rabbit Polyclonal anti-BAG5 antibody is suitable to detect BAG5 in samples from Rat. It has been validated for WB and IHC (p).

Quick Overview for BAG5 antibody (ABIN306923)

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAG5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-BAG5 Antibody

Purpose: Rabbit anti Rat BAG-5

Cross-Reactivity: Rat

Characteristics: It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp7079s anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the human BAG-5 protein.

Application Details

Application Notes: Anibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for BAG5

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Alternative Name: BAG-5

UniProt: Q9UL15

Pathways: SARS-CoV-2 Protein Interactome