SNAP25 antibody

Catalog No. ABIN306924

The Mouse Monoclonal anti-SNAP25 antibody (Clone S-7B8) (ABIN306924) specifically detects SNAP25 in WB, ICC and IHC (p). The antibody is reactive with Human, Rat, Mouse, Cow, Chicken and Monkey samples.

Quick Overview for SNAP25 antibody (ABIN306924)

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reactivity: Human, Rat, Mouse, Cow, Chicken, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNAP25 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: S-7B8

Product Details anti-SNAP25 Antibody

Purpose: Mouse anti Rat SNAP25

Cross-Reactivity: Chicken, Cow, Human, Monkey, Mouse, Rat

Characteristics: SNAP25 (Synaptosome-Associated Protein of 25 kDa) is a membrane bound, pre-synaptic nerve terminal protein that plays an essential role in synaptic vesicle fusion and exocytosis. It is involved in the molecular regulation of neurotransmitter release. It is thought to play an important role in the synaptic function of specific neuronal systems. SNAP25 associates with proteins involved in vesicle docking and membrane fusion. SNAP25 exists as two alternatively spliced isoforms, SNAP25A and SNAP25B. These isoforms are differentially expressed in neurons and neuroendocrine cells. These two isoforms differ by 9 amino acids in the central portion of the protein.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Antibody can be used for Western blotting (1-5 μg/mL), immunocytochemistry and immunohistochemistry on paraformaldehyde fixed CNS tissues (1-5 μg/mL). Does not stain reduced proteins. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SNAP25

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Alternative Name: SNAP25

Background: Synaptosome-Associated Protein of 25 kDa

UniProt: P60880

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport