SGPP1 antibody

Catalog No. ABIN306934

This Rabbit Polyclonal antibody specifically detects SGPP1 in WB. It exhibits reactivity toward Human.

Quick Overview for SGPP1 antibody (ABIN306934)

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGPP1 Antibody

Cross-Reactivity: Human

Characteristics: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.

Purification: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 1 protein.

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (1:200 dilution). Tissue lysate should be used at 10-50 μg/lane. Other applications not yet tested. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Provided as ligand affinity purified antibody in phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for SGPP1

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Alternative Name: Sphingosine 1-Phosphate Phosphatase 1

UniProt: Q9BX95