Sphingomyelin Synthase 1 antibody

Catalog No. ABIN306949

This Rabbit Polyclonal antibody specifically detects Sphingomyelin Synthase 1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Sphingomyelin Synthase 1 antibody (ABIN306949)

Target: Sphingomyelin Synthase 1 (SGMS1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sphingomyelin Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Sphingomyelin Synthase 1 Antibody

Purpose: Rabbit anti Human Sphingomyelin Synthase 1 (Peptide as antigen)

Characteristics: A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.

Purification: High Salt Precipitation

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/ml

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for Sphingomyelin Synthase 1

Target: Sphingomyelin Synthase 1 (SGMS1)

Alternative Name: Sphingomyelin Synthase 1

Background: Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin