Sphingomyelin Synthase 1 antibody

Catalog No. ABIN306949

Product Details anti-Sphingomyelin Synthase 1 Antibody

Target: Sphingomyelin Synthase 1 (SGMS1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sphingomyelin Synthase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Brain, heart, kidney, liver, muscle and stomach..

Restrictions: For Research Use only

Handling

Concentration: 1 mg/ml

Storage: -20 °C

Target Details for Sphingomyelin Synthase 1

Target: Sphingomyelin Synthase 1 (SGMS1)

Alternative Name: Sphingomyelin Synthase 1 (SGMS1 Products)

Synonyms: MGC81436 antibody, TMEM23 antibody, MOB antibody, MOB1 antibody, SMS1 antibody, hmob33 antibody, 9530058O11Rik antibody, AI841905 antibody, C80702 antibody, Mob antibody, Sms1 antibody, Sor1 antibody, Tmem23 antibody, sphingomyelin synthase 1 antibody, sphingomyelin synthase 1 S homeolog antibody, phosphatidylcholine:ceramide cholinephosphotransferase 1 antibody, SGMS1 antibody, sgms1.S antibody, LOC100013212 antibody, Sgms1 antibody

Background: A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach. Synonyms: Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein.

UniProt: Q86VZ5

Pathways: Cellular Response to Molecule of Bacterial Origin