VEGFR2/CD309 antibody (AA 1158-1345)

Catalog No. ABIN307656

This anti-VEGFR2/CD309 antibody is a Mouse Monoclonal antibody detecting VEGFR2/CD309 in WB, IHC, ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for VEGFR2/CD309 antibody (AA 1158-1345) (ABIN307656)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This VEGFR2/CD309 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VEGFR2/CD309 Antibody

Binding Specificity: AA 1158-1345

Specificity: Recognizes mouse Vascular Endothelial Growth Factor Receptor 2 (VEGF R2, also known as FLK-1). This Recognizes KDR - human VEGF R2. VEGF R2 is one of three VEGF receptor kinases which plays an important role in angiogenesis. VEGF receptors are characterized by a cytoplasmic split-kinase domain and seven extracellular immunoglobulin domains.

Purification: Protein A purified

Immunogen: Recombinant fragment corresponding to amino acids 1158 to 1345 (the intracellular region) of mouse VEGF Receptor 2.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, IHC, IHC-P, WB

Usage: Western Blot: LS-C45503 detects bands of approximately 200kD and 230kD in HUVEC cell lysates. Immunohistology: This product requires pre-treatment of paraffin sections. EDTA  pH 8.0 is recommended for this purpose.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Alternative Name: KDR / VEGFR2

Background: Name/Gene ID: KDR
Subfamily: VEGF Receptor
Family: Protein Kinase

Synonyms: KDR, CD309, Fetal liver kinase 1, Fetal liver kinase-1, FLK-1, FLK1, Kinase insert domain receptor, Quek1, VEGFR, VEGFR2, Soluble VEGFR2, VEGF receptor 2, VEGFR-2, CD309 antigen, VEGF-R2

Gene ID: 3791

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling