CD11b antibody (PE)

Catalog No. ABIN307829

The Rat Monoclonal anti-CD11b antibody has been validated for FACS. It is suitable to detect CD11b in samples from Mouse.

Quick Overview for CD11b antibody (PE) (ABIN307829)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD11b antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: M1-70-15

Product Details anti-CD11b Antibody (PE)

Specificity: Anti-mouse CD1 1b (MAC-1) (Ly 40) monoclonal antibody is specific for the 170 kD a subunit of MAC-1, which mediates adhesion to ICAM-1 (CD54) and C3bi. Mac-1 is expressed on granulocytes, macrophages, natural killer cells, and B-1 cells in the peritoneal.

Purification: Protein G purified

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG2b

Application Details

Application Notes: Approved: Flo (0.1 μg/10 x10⁶)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, EIA grade BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Dilute only prior to immediate use. Freezing PE conjugates will result in a substantial loss of enzymatic activity.

Storage: 4 °C

Storage Comment: Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing PE conjugates will result in a substantial loss of enzymatic activity.

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: ITGAM / CD11b

Background: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gene ID: 3684

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation