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P-Selectin antibody

SELP Reactivity: Human, Pig, Sheep FACS, IP, IHC (p) Host: Mouse Monoclonal Psel-KO-2-5 unconjugated
Catalog No. ABIN316863
  • Target See all P-Selectin (SELP) Antibodies
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Reactivity
    • 111
    • 36
    • 32
    • 21
    • 13
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Pig, Sheep
    Host
    • 70
    • 57
    • 1
    • 1
    Mouse
    Clonality
    • 67
    • 62
    Monoclonal
    Conjugate
    • 57
    • 17
    • 15
    • 10
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This P-Selectin antibody is un-conjugated
    Application
    • 83
    • 69
    • 30
    • 30
    • 29
    • 25
    • 13
    • 13
    • 12
    • 10
    • 10
    • 9
    • 9
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody recognises the CD62P cell surface antigen, a 140 kDa glycoprotein also known as P-selectin.
    Characteristics
    Synonyms: SELP, GMRP, GRMP, PADGEM, GMP-140, LECAM3, Granule membrane protein 140,Leukocyte-endothelial cell adhesion molecule 3, CD62 antigen-like family member P
    Purification
    Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
    Immunogen
    CD62P transfected 300. 19 cells.
    Clone
    Psel-KO-2-5
    Isotype
    IgG1
    Top Product
    Discover our top product SELP Primary Antibody
  • Application Notes
    Immunoprecipitation. Flow Cytometry: Use 10 μL of 1/1-1/50 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Alternative Name
    CD62P / P-Selectin (SELP Products)
    Synonyms
    PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
    Background
    SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells.Synonyms: CD62 antigen-like family member P, GMP-140, GMRP, GRMP, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, PADGEM, SELP
    Gene ID
    6403
    UniProt
    P16109
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