SLC44A1 antibody

Catalog No. ABIN316971

The Mouse Monoclonal anti-SLC44A1 antibody is suitable to detect SLC44A1 in samples from Human. It has been validated for FACS, IP and IHC (fro).

Quick Overview for SLC44A1 antibody (ABIN316971)

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC44A1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: VIM-15b

Product Details anti-SLC44A1 Antibody

Specificity: This antibody is specific for the C-terminal variant of Human CDw92 (isoform 3), also known as CTL1. Clone VIM-15b is reported to augment the LPS-induced production of IL-10 by monocyte-derived dendritic cells (Mo-DCs), and the reduced expression of CDw92 by Mo-DCs treated with ionomycin or calcium ionophore, can be reinduced in the presence of IL-10.

Characteristics: Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

Immunogen: MV4-11 acute monocyte leukaemia cells.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry: 1/50 - 1/200. Immunohistochemistry on frozen sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by

Expiry Date: 12 months

Target Details for SLC44A1

Target: SLC44A1 (Solute Carrier Family 44, Member 1 (SLC44A1))

Alternative Name: CD92 / SLC44A1

Background: CDw92 is a 70 kDa multi-pass membrane protein, expressed by monocytes, neutrophils, certain myeloid and T cell lines, and weakly by endothelial cells, fibroblasts and epithelial cells. CDw92 is a member of the choline transporter-like protein family, so called due to their involvement in the efficient supply/transport of the natural amine choline, a vital cell nutrient required for the synthesis of cell membrane phospholipid components and the neurotransmitter acetylcholine.Synonyms: CDw92, CTL1, Choline transporter-like protein 1, Solute carrier family 44 member 1

Gene ID: 23446

UniProt: Q8WWI5