IL1A antibody

Catalog No. ABIN317141

Product Details anti-IL1A Antibody

Target: IL1A (Interleukin 1 alpha (IL1A))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL1A antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificity: This antibody specifically recognises interleukin-1 alpha (IL-1 alpha). Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/mL of recombinant mouse IL-1 alpha by 95 % , as tested using mouse D10(N4)M T-helper cells.

Characteristics: Synonyms: IL-1 alpha, IL1F1, IL1A, Hematopoietin-1

Purification: Purified IgG prepared by affinity chromatography

Immunogen: Recombinant mouse IL-1 alpha

Clone: Flo1

Isotype: IgG1

Application Details

Application Notes: ELISA. Functional Assays: 50g/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Phosphate buffered saline

Preservative: Azide free

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Alternative Name: Interleukin-1 alpha / IL-1A (IL1A Products)

Synonyms: IL-1A antibody, IL1 antibody, IL1-ALPHA antibody, IL1F1 antibody, IL-6 antibody, Il-1a antibody, IL-1 alpha antibody, IL-1alpha antibody, L1A antibody, interleukin 1 alpha antibody, interleukin 6 antibody, IL1A antibody, IL6 antibody, Il1a antibody

Background: IL-1 alpha is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.Synonyms: Hematopoietin-1, IL-1 alpha, IL1A, IL1F1

Gene ID: 16175

UniProt: P01582

Pathways: NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints