Cathepsin D antibody (AA 21-412)
Quick Overview for Cathepsin D antibody (AA 21-412) (ABIN317502)
Target
See all Cathepsin D (CTSD) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 21-412
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Specificity
- The antibody recognizes Human Cathepsin D. Other species not tested.
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Characteristics
- Synonyms: CTSD, CPSD
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Purification
- Protein-G affinity chromatography
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Immunogen
- Recombinant human Cathepsin D (21-412 aa) purified from E. coli
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Isotype
- IgG2b
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Application Notes
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ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on paraffin-embedded tissues (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- Cathepsin D (CTSD)
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Alternative Name
- Cathepsin D
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Background
- The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D.Synonyms: CPSD, CTSD
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Gene ID
- 1509
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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