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Cathepsin D antibody (AA 21-412)

The Mouse Monoclonal anti-Cathepsin D antibody (Clone 4G2) (ABIN317502) specifically detects Cathepsin D in WB, IHC (p) and EIA. The antibody is reactive with Human samples.
Catalog No. ABIN317502
$583.20
Plus shipping costs $50.00
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Quick Overview for Cathepsin D antibody (AA 21-412) (ABIN317502)

Target

See all Cathepsin D (CTSD) Antibodies
Cathepsin D (CTSD)

Reactivity

  • 167
  • 56
  • 36
  • 6
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Human

Host

  • 118
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Mouse

Clonality

  • 95
  • 91
Monoclonal

Conjugate

  • 112
  • 14
  • 7
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  • 3
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This Cathepsin D antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone

4G2
  • Binding Specificity

    • 45
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    AA 21-412

    Specificity

    The antibody recognizes Human Cathepsin D. Other species not tested.

    Characteristics

    Synonyms: CTSD, CPSD

    Purification

    Protein-G affinity chromatography

    Immunogen

    Recombinant human Cathepsin D (21-412 aa) purified from E. coli

    Isotype

    IgG2b
  • Application Notes

    ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on paraffin-embedded tissues (1: 50).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, 0.09 % Sodium Azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    Expiry Date

    12 months
  • Target

    Cathepsin D (CTSD)

    Alternative Name

    Cathepsin D

    Background

    The aspartic protease cathepsin D is one of the major proteolytic enzymes in lysosomes. The cathepsin D gene locates on chromosome 11p15.5 and spans approximately 11 kb with nine exons. Initially synthesized as an inactive precursor of pro-cathepsin D, the enzyme is subsequently converted to its active forms by proteolytic processing. Breast cancer cells, unlike normal cells, secrete high levels of pro-cathepsin D.Synonyms: CPSD, CTSD

    Gene ID

    1509

    UniProt

    P07339

    Pathways

    Peptide Hormone Metabolism
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