UNG antibody (N-Term)

Catalog No. ABIN317576

The Mouse Monoclonal anti-UNG antibody is suitable to detect UNG in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for UNG antibody (N-Term) (ABIN317576)

Target: UNG (Uracil-DNA Glycosylase (UNG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UNG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: K1C12

Product Details anti-UNG Antibody

Binding Specificity: AA 1-313, N-Term

Specificity: The antibody recognizes Human UNG. Other species not tested.

Characteristics: Synonyms: UDG, DGU, UNG1, UNG15

Purification: Protein-G affinity chromatography

Immunogen: Recombinant Human UNG (1-313 aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1/1,000-1/2,000)Immunohistochemistry on Paraffin Sections (10 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for UNG

Target: UNG (Uracil-DNA Glycosylase (UNG))

Background: The human UNG gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms of uracil-DNA glycosylase (UNG). These forms are generated from transcription from alternative promoters, promoter A and promoter B respectively, and the subsequent use of alternative splicing. UNG is responsible for the removal of uracil from DNA by hydrolysis of the N-glycosidic bond that links the base to the deoxyribose backbone, leaving an abasic site. UNG is a highly conserved enzyme found in many species.Synonyms: DGU, UDG, UNG1, UNG15

Gene ID: 7374

UniProt: P13051

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response