VIPR1 antibody

Catalog No. ABIN317871

Product Details anti-VIPR1 Antibody

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VIPR1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of VPAC1 protein. (region surrounding Val371)

Purification: Affinity chromatography

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for VIPR1

Target: VIPR1 (Vasoactive Intestinal Peptide Receptor 1 (VIPR1))

Abstract: VIPR1 Products

Synonyms: HVR1 antibody, II antibody, PACAP-R-2 antibody, PACAP-R2 antibody, RDC1 antibody, V1RG antibody, VAPC1 antibody, VIP-R-1 antibody, VIPR antibody, VIRG antibody, VPAC1 antibody, VPAC1R antibody, VPCAP1R antibody, CVIPR antibody, AV071699 antibody, VIP-R1 antibody, RATVASREC antibody, VASREC antibody, VIPR1 antibody, LOC100226500 antibody, vipr1 antibody, hvr1 antibody, rdc1 antibody, v1rg antibody, vipr antibody, virg antibody, vapc1 antibody, vpac1 antibody, vpcap1 antibody, vpac1-r antibody, VIP-R antibody, vasoactive intestinal peptide receptor 1 antibody, vasoactive intestinal peptide receptor 1b antibody, vasoactive intestinal peptide receptor 1 S homeolog antibody, vasoactive intestinal polypeptide receptor antibody, VIPR1 antibody, Vipr1 antibody, vipr1b antibody, vipr1 antibody, vipr1.S antibody, LOC100303683 antibody

Background: The vasoactive intestinal peptide (VIP) and the pituitary adenylate cylaseactivating polypeptide (PACAP) belong to a superfamily of peptide hormones that include glucagon, secretin and growth hormone releasing hormone. The effects of VIP and PACAP are mediated by three G-protein coupled receptors, VPAC1, VPAC2 and the PACAP receptor (also designated PAC1-R). The VPAC receptors have equal affinities for VIP and PACAP, which stimulate the activation of adenylyl cyclase. Both VPAC1, a 47 kDa protein, and VPAC2, a 65 kDa protein, are abundantly expressed in brain and T cells, where they modulate neuronal differentiation and T cell activation, respectively. The PACAP receptor is a seven transmembrane protein that produces at least eight isoforms by alternative splicing. Each isoform is associated with a specific signaling pathway and a specific expression pattern. The PACAP receptor, which is thought to play an integral role in brain development, preferentially binds PACAP in order to stimulate a cAMP-protein kinase A signaling pathway.Synonyms: PACAP-R-2, PACAPR2, Pituitary adenylate cyclase-activating polypeptide type II receptor, VIP-R1, VIPR-1, VIPR1, Vasoactive intestinal polypeptide receptor 1

Molecular Weight: approx. 52 kDa

Gene ID: 7433

NCBI Accession: NP_004615

UniProt: P32241