IRS1 antibody (pSer312)

Catalog No. ABIN3182459

This Rabbit Polyclonal antibody specifically detects IRS1 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IRS1 antibody (pSer312) (ABIN3182459)

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-IRS1 Antibody

Binding Specificity: pSer312

Specificity: Phospho-IRS-1 (S312) Polyclonal Antibody detects endogenous levels of IRS-1 protein only when phosphorylated at S312.

Characteristics: Rabbit Polyclonal to Phospho-IRS-1 (S312).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human IRS-1 around the phosphorylation site of S312.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:20000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Alternative Name: IRS-1

Molecular Weight: 170/132 kDa

Gene ID: 3667

UniProt: P35568

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process