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IRF7 antibody (Middle Region)

IRF7 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN318752
  • Target See all IRF7 Antibodies
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    Binding Specificity
    • 17
    • 17
    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 70
    • 55
    • 54
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 69
    • 2
    Rabbit
    Clonality
    • 58
    • 13
    Polyclonal
    Conjugate
    • 24
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IRF7 antibody is un-conjugated
    Application
    • 50
    • 18
    • 15
    • 14
    • 14
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Specificity
    This antibody detects Human Interferon Regulatory Factor 7 (IRF7). Other species not tested.
    Purification
    Affinity Chromatography
    Immunogen
    14 amino acid peptide sequence near the center of Human IRF7.
    Isotype
    IgG
    Top Product
    Discover our top product IRF7 Primary Antibody
  • Application Notes
    Western Blot: 0.5 - 1.0g/mL, detects a band of approximately 51 kDa in 293 whole celllysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    Alternative Name
    IRF7 (IRF7 Products)
    Synonyms
    wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
    Background
    IRF7 is a 54kD transcriptional activator of type I interferons (IFNalpha/beta) in response to local and systemic viral infection. IRF7 is mostly expressed by plasmacytoid dendritic cells (pDC), which differentiate in response to IFNs and virus infection. This then stabilizes the IRF7 protein, in turn leading to increased IFN production. Multiple IRF7 transcript variants have been identified, although their individual functions have not yet been established.Synonyms: IRF-7, Interferon regulatory factor 7
    Gene ID
    3665
    NCBI Accession
    NP_001563
    UniProt
    Q92985
    Pathways
    TLR Signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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