SLPI antibody (Middle Region)

Catalog No. ABIN318889

This Rabbit Polyclonal antibody specifically detects SLPI in WB and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for SLPI antibody (Middle Region) (ABIN318889)

Target: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLPI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SLPI Antibody

Binding Specificity: Middle Region

Purification: Purified

Immunogen: A 17 amino acid peptide located near the centre of human SLPI.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1.0 - 2.0g/mL, detects a band of approximately 14 kDa in Daudi cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLPI

Target: SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))

Alternative Name: Antileukoproteinase (ALP)

Background: SLPI is a 14kD non-glycosylated protein produced by secretory cells in the respiratory, genital and lacrimal glands, and by macrophages, B-cells and neutrophils. The functions of SLPI are diverse. The SLPI protein inhibits protease activity at sites of inflammation, protecting tissues against protease mediated damage and it possesses anti-microbial/anti-viral activity. In addition, SLPI has been reported to exhibit anti-inflammatory properties, regulating lipopolysaccharide induced activation of NF-kappa beta in peripheral blood monocytes.Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4

Gene ID: 9606

UniProt: P03973