Glutamate Receptor 1 antibody (pSer831)

Catalog No. ABIN319113

The Rabbit Polyclonal anti-Glutamate Receptor 1 antibody (ABIN319113) specifically detects Glutamate Receptor 1 in WB. The antibody is reactive with Human, Rat, Mouse, Chicken and Dog samples.

Quick Overview for Glutamate Receptor 1 antibody (pSer831) (ABIN319113)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Human, Rat, Mouse, Chicken, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: pSer831

Specificity: This antibody is specific for glutamate receptor subunit 1 (GluR1) when phosphorylated at serine 831.

Purification: Affinity chromatography

Immunogen: Synthetic phosphopeptide corresponding to amino acid sequence within GluR1 which includes phosphorylated Ser831.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 1000, detects a band of approximately 100 kDa in rat brain lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES, pH 7.5 containing 0.09 % Sodium Azide, 0.01 % Bovine Serum Albumin and 50 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: Glutamate Receptor 1 / GLUR1

Background: GluR1, widely expressed throughout the nervous system, is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses. Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gene ID: 2890

NCBI Accession: NP_000818

UniProt: P42261

Pathways: PI3K-Akt Signaling