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p53 antibody (Ser37)

The Rabbit Polyclonal anti-p53 antibody has been validated for WB. It is suitable to detect p53 in samples from Human.
Catalog No. ABIN319308

Quick Overview for p53 antibody (Ser37) (ABIN319308)

Target

See all p53 (TP53) Antibodies
p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This p53 antibody is un-conjugated

Application

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Western Blotting (WB)
  • Binding Specificity

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    Ser37

    Specificity

    This antibody detects endogenous levels of total p53 protein.

    Purification

    Immunoaffinity Chromatography.

    Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of Serine 37 (L-P-SP-Q-A).
  • Application Notes

    Western Blot (1/500-1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C

    Storage Comment

    Store the antibody (in aliquots) at-20 °C.
  • Target

    p53 (TP53) (Tumor Protein P53 (TP53))

    Alternative Name

    p53 (TP53)

    Background

    Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53

    Gene ID

    7157

    NCBI Accession

    NP_000537

    UniProt

    P04637

    Pathways

    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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