Paxillin antibody (pSer17)
Quick Overview for Paxillin antibody (pSer17) (ABIN325038)
Target
See all Paxillin (PXN) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer17
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Specificity
- Detects a 68kD protein corresponding to the molecular weight of phosphorylated paxillin on SDS-PAGE immunoblots of EGF treated A431 cells, but not in A431 control cells. Similar results were seen in calyculin A treated human A431 and aortic endothelial cells. Epitope: phosphoserine 178. Species cross Reactivity: Human. This human sequence is highly conserved in rat and mouse paxillin.
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Purification
- Immunoaffinity purified
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Immunogen
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Synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 178 of human paxillin. This human sequence is highly conserved in rat and mouse paxillin.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG
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Application Notes
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Approved: ELISA (1:2000), WB (1:500)
Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1:500. ELISA: 1:2000. -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Paxillin (PXN)
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Alternative Name
- PXN / Paxillin
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Background
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Name/Gene ID: PXN
Synonyms: PXN, Paxillin -
Gene ID
- 5829
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UniProt
- P49023
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Pathways
- MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Target
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