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Paxillin antibody (pSer17)

This anti-Paxillin antibody is a Rabbit Polyclonal antibody detecting Paxillin in WB and ELISA. Suitable for Human.
Catalog No. ABIN325038

Quick Overview for Paxillin antibody (pSer17) (ABIN325038)

Target

See all Paxillin (PXN) Antibodies
Paxillin (PXN)

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Paxillin antibody is un-conjugated

Application

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Western Blotting (WB), ELISA
  • Binding Specificity

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    pSer17

    Specificity

    Detects a 68kD protein corresponding to the molecular weight of phosphorylated paxillin on SDS-PAGE immunoblots of EGF treated A431 cells, but not in A431 control cells. Similar results were seen in calyculin A treated human A431 and aortic endothelial cells. Epitope: phosphoserine 178. Species cross Reactivity: Human. This human sequence is highly conserved in rat and mouse paxillin.

    Purification

    Immunoaffinity purified

    Immunogen

    Synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 178 of human paxillin. This human sequence is highly conserved in rat and mouse paxillin.

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG
  • Application Notes

    Approved: ELISA (1:2000), WB (1:500)

    Usage: Suitable for use in Western Blot and ELISA. Western Blot: 1:500. ELISA: 1:2000.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    Paxillin (PXN)

    Alternative Name

    PXN / Paxillin

    Background

    Name/Gene ID: PXN

    Synonyms: PXN, Paxillin

    Gene ID

    5829

    UniProt

    P49023

    Pathways

    MAPK Signaling, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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