CXCR7 antibody (APC)

Catalog No. ABIN332284

Product Details anti-CXCR7 Antibody (APC)

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR7 antibody is conjugated to APC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes the five distinct human CXCR7 transfectants, but not their respective parental lines. It also reacts with MCF-7 cells expression of CXCR7. This antibody does not react with monocytes or lymphocytes by flow cytometry. An underestimation of CXCR7 expression on certain cell types has been reported.

Purification: Protein G purified

Immunogen: Human CXCR7 encoding plasmid.

Type of Immunogen: Purified protein

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (50 μg/mL), IHC, IHC-P

Usage: Suitable for use in Flow Cytometry and Immunohistochemistry. Flow Cytometry: 50 μg/mL 10 μL labels 1-2.5x10^5 cells in a total reaction volume not exceeding 200 μL. Immunohistochemistry (paraffin sections): 8-25 μg/mL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile PBS

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose.

Handling Advice: avoid freeze thaw cycles.

Storage: -20 °C

Storage Comment: Lyophilized and resuspended forms: store at -20°C.

Target Details for CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Alternative Name: ACKR3 / CXCR7 (CXCR7 Products)

Synonyms: CMKOR1 antibody, CXC-R7 antibody, CXCR-7 antibody, CXCR7 antibody, GPR159 antibody, RDC-1 antibody, RDC1 antibody, AW541270 antibody, Cmkor1 antibody, Cxcr7 antibody, Rdc1 antibody, ackr3 antibody, cxcr7 antibody, rdc1 antibody, xcxcr7 antibody, atypical chemokine receptor 3 antibody, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 antibody, atypical chemokine receptor 3 L homeolog antibody, ACKR3 antibody, MmrVgp88 antibody, Ackr3 antibody, ackr3.L antibody

Background: Name/Gene ID: ACKR3
Subfamily: Chemokine
Family: GPCR

Synonyms: ACKR3, Chemokine orphan receptor 1, CMKOR1, CXCR7, CXC-R7, GPRN1, RDC1, RDC-1, CXCR-7, G-protein coupled receptor 159, GPR159

Gene ID: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling