FGFR2 antibody (Internal Region)

Catalog No. ABIN334399

This Goat Polyclonal antibody specifically detects FGFR2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for FGFR2 antibody (Internal Region) (ABIN334399)

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This FGFR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-FGFR2 Antibody

Binding Specificity: Internal Region

Purpose: FGFR2

Sequence: GREKEITASP DY

Specificity: This antibody is expected to recognise all reported isoforms except isoform 7 (NP_001138389.1). The immunizing peptide represents part of the extracellular domain.

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence according to NP_000132.3, NP_075259.4, NP_001138385.1, NP_001138386.1, NP_001138387.1, NP_001138388.1, NP_001138390.1, NP_001138391.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 100 kDa band observed in Human lysates of cell line A549 (calculated MW of 92.0 kDa according to NP_000132.1 and of 92.1 kDa according to NP_075259.2). Recommended concentration: 0.3-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:64000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for FGFR2

Target: FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))

Alternative Name: FGFR2

Background: FGFR2 , fibroblast growth factor receptor 2, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25, BEK fibroblast growth factor receptor, FGF receptor, FGFR-2, bacteria-expressed kinase, hydroxyaryl-protein kinase, keratinocyte grow

Gene ID: 2263, 14183, 25022

NCBI Accession: NP_000132, NP_075259, NP_001138385, NP_001138386, NP_001138387, NP_001138388, NP_001138390, NP_001138391

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding