Abeta 1-42 antibody

Catalog No. ABIN334634

Product Details anti-Abeta 1-42 Antibody

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This Abeta 1-42 antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Cross-Reactivity (Details): Not reactive in: no confirmed exceptions from predicted reactivity known in the moment

Predicted Reactivity: bovine, chicken, dog, porcine, rabbit

Characteristics: Expected / apparent Molecular Weight of the Antigene: 4.5 kDa

Purification: affinity purified

Immunogen: synthetic peptide chosen from human Abeta (1-42) protein. Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A

Isotype: IgY

Application Details

Application Notes: 1:500 (ELISA), 1:1000 (Dot)

Comment:

the antibody can detect Abeta(1-42), but does not react with Abeta(1-40), Abeta(1-41), Abeta(1-28) Abeta(1-20) or Abeta(1-17)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 8.0 + 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Make aliquots to avoid repreated freeze-thaw cycles and working with a stock.

Storage: 4 °C

Storage Comment: store at 4°C, make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.

Target Details for Abeta 1-42

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Alternative Name: Amyloid-beta 42 protein (Abeta (1-42)) (Abeta 1-42 Products)

Synonyms: amyloid beta precursor protein antibody, App antibody, APP antibody

Background: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067

Molecular Weight: 4.5 kDa